High Constitutive Cytokine Release by Primary Human Acute Myeloid Leukemia Cells Is Associated with a Specific Intercellular Communication Phenotype

High Constitutive Cytokine Release by Primary Human Acute Myeloid Leukemia Cells Is Associated with a Specific Intercellular Communication Phenotype

Acute myeloid leukemia (AML) is a heterogeneous disease, and this heterogeneity includes the capacity of constitutive release of extracellular soluble mediators by AML cells. We investigated whether this capacity is associated with molecular genetic abnormalities, and we compared the proteomic profi...

Full description

Bibliographic Details
Main Authors: Håkon Reikvam, Elise Aasebø, Annette K. Brenner, Sushma Bartaula-Brevik, Ida Sofie Grønningsæter, Rakel Brendsdal Forthun, Randi Hovland, Øystein Bruserud
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Journal of Clinical Medicine
Subjects:
acute myeloid leukemia
gene mutations
differentiation
cytokines
proteomic profile
integrin
RAC1
SYK
Online Access:https://www.mdpi.com/2077-0383/8/7/970

Internet

https://www.mdpi.com/2077-0383/8/7/970

Similar Items