Complement Inhibitor Therapy for Myasthenia Gravis

Complement activation as a driver of pathology in myasthenia gravis (MG) has been appreciated for decades. The terminal complement component [membrane attack complex (MAC)] is found at the neuromuscular junctions of patients with MG. Animals with experimental autoimmune MG are dependent predominantl...

Full description

Bibliographic Details
Main Authors: Khaled Albazli, Henry J. Kaminski, James F. Howard
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
C5
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00917/full