Participation of the NO/cGMP/K+ATP pathway in the antinociception induced by Walker tumor bearing in rats

Participation of the NO/cGMP/K+ATP pathway in the antinociception induced by Walker tumor bearing in rats

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Implantation of Walker 256 tumor decreases acute systemic inflammation in rats. Inflammatory hyperalgesia is one of the most important events of acute inflammation. The L-arginine/NO/cGMP/K+ATP pathway has been proposed as the mechanism of peripheral antinociception mediated by several drugs and phy...

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Bibliographic Details
Main Authors: A.L.R. Barbosa, C.A. Pinheiro, G.J. Oliveira, J.N.L. Torres, M.O. Moraes, R.A. Ribeiro, M.L. Vale, M.H.L.P. Souza
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Walker 246 tumor-bearing rats
Hypernociception
Nitric oxide
Carrageenan
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000600009&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000600009&lng=en&tlng=en

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