The Relationship of Secretion and Activity of Recombinant Factor IX with N-Glycosylation

Background:  Human coagulation factor IX (hFIX) is a glycoprotein with two N-glycosylation sites at the activation peptide. Since the activation peptide is removed in mature hFIX, the exact role of N-glycosylation is unclear. To investigate the role of N-glycosylation in the secretion and activity o...

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Bibliographic Details
Main Authors: Samira Khalilzadeh, Jafar Vatandoost
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences and Health Services 2020-02-01
Series:Research in Molecular Medicine
Subjects:
Online Access:http://rmm.mazums.ac.ir/article-1-345-en.html