Autophagy creates a CTL epitope that mimics tumor-associated antigens.

Autophagy creates a CTL epitope that mimics tumor-associated antigens.

The detailed mechanisms responsible for processing tumor-associated antigens and presenting them to CTLs remain to be fully elucidated. In this study, we demonstrate a unique CTL epitope generated from the ubiquitous protein puromycin-sensitive aminopeptidase, which is presented via HLA-A24 on leuke...

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Bibliographic Details
Main Authors: Ayako Demachi-Okamura, Hiroki Torikai, Yoshiki Akatsuka, Hiroyuki Miyoshi, Tamotsu Yoshimori, Kiyotaka Kuzushima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3469533?pdf=render

Internet

http://europepmc.org/articles/PMC3469533?pdf=render

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