DNA Methylation Signature of Epileptic Encephalopathy-Related Pathogenic Genes Encoding Ion Channels in Temporal Lobe Epilepsy

DNA Methylation Signature of Epileptic Encephalopathy-Related Pathogenic Genes Encoding Ion Channels in Temporal Lobe Epilepsy

Epilepsy is characterized by highly abnormal synchronous discharge of brain neurons, and ion channels are fundamental in the generation and modulation of neural excitability. Considering that abnormal methylation can either activate or repress genes, this study was designed to explore the DNA methyl...

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Bibliographic Details
Main Authors: Hua Tao, Zengqiang Chen, Jianhao Wu, Jun Chen, Yusen Chen, Jiawu Fu, Chaowen Sun, Haihong Zhou, Wangtao Zhong, Xu Zhou, Keshen Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neurology
Subjects:
DNA methylation
epigenetic
temporal lobe epilepsy
genetic susceptibility
ion channels
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.692412/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.692412/full

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