Synapto-protective drugs evaluation in reconstructed neuronal network.

Chronic neurodegenerative syndromes such as Alzheimer's and Parkinson's diseases, or acute syndromes such as ischemic stroke or traumatic brain injuries are characterized by early synaptic collapse which precedes axonal and neuronal cell body degeneration and promotes early cognitive impai...

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Main Authors: Bérangère Deleglise, Benjamin Lassus, Vaneyssa Soubeyre, Aurélie Alleaume-Butaux, Johannes J Hjorth, Maéva Vignes, Benoit Schneider, Bernard Brugg, Jean-Louis Viovy, Jean-Michel Peyrin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3745451?pdf=render