Chitosan hydrogel incorporated with dental pulp stem cell-derived exosomes alleviates periodontitis in mice via a macrophage-dependent mechanism

Periodontitis is caused by host immune-inflammatory response to bacterial insult. A high proportion of pro-inflammatory macrophages to anti-inflammatory macrophages leads to the pathogenesis of periodontitis. As stem cell-derived exosomes can modulate macrophage phenotype, dental pulp stem cell-deri...

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Bibliographic Details
Main Authors: Zongshan Shen, Shuhong Kuang, Yong Zhang, Mingmei Yang, Wei Qin, Xuetao Shi, Zhengmei Lin
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-12-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20301298