Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development

Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development

An ‘interactome’ screen of all Drosophila cell-surface and secreted proteins containing immunoglobulin superfamily (IgSF) domains discovered a network formed by paralogs of Beaten Path (Beat) and Sidestep (Side), a ligand-receptor pair that is central to motor axon guidance. Here we describe a new m...

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Bibliographic Details
Main Authors: Hanqing Li, Ash Watson, Agnieszka Olechwier, Michael Anaya, Siamak K Sorooshyari, Dermott P Harnett, Hyung-Kook (Peter) Lee, Jost Vielmetter, Mario A Fares, K Christopher Garcia, Engin Özkan, Juan-Pablo Labrador, Kai Zinn
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
protein-protein interaction
interactome
immunglobulin superfamily
neural development
motor neuron
motor axon guidance
Online Access:https://elifesciences.org/articles/28111

Internet

https://elifesciences.org/articles/28111

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