Gene repression via multiplex gRNA strategy in Y. lipolytica

Gene repression via multiplex gRNA strategy in Y. lipolytica

Abstract Background The oleaginous yeast Yarrowia lipolytica is a promising microbial cell factory due to their biochemical characteristics and native capacity to accumulate lipid-based chemicals. To create heterogenous biosynthesis pathway and manipulate metabolic flux in Y. lipolytica, numerous st...

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Bibliographic Details
Main Authors: Jin-lai Zhang, Yang-Zi Peng, Duo Liu, Hong Liu, Ying-Xiu Cao, Bing-Zhi Li, Chun Li, Ying-Jin Yuan
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Microbial Cell Factories
Subjects:
CRISPR interference
Multiplex gene repression
Yarrowia lipolytica
Synthetic biology
Online Access:http://link.springer.com/article/10.1186/s12934-018-0909-8

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http://link.springer.com/article/10.1186/s12934-018-0909-8

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