An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere formation.

Hairpin telomeres of bacterial linear chromosomes are generated by a DNA cutting-rejoining enzyme protelomerase. Protelomerase resolves a concatenated dimer of chromosomes as the last step of chromosome replication, converting a palindromic DNA sequence at the junctions between chromosomes into cova...

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Bibliographic Details
Main Authors: Ke Shi, Wai Mun Huang, Hideki Aihara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3558466?pdf=render