HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway.

HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway.

Tubular cell HIV-infection has been reported to manifest in the form of cellular hypertrophy and apoptosis. In the present study, we evaluated the role of mammalian target of rapamycin (mTOR) pathway in the HIV induction of tubular cell protein synthesis. Mouse proximal tubular epithelial cells (MPT...

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Bibliographic Details
Main Authors: Shabina Rehman, Mohammad Husain, Anju Yadav, Balakuntalam S Kasinath, Ashwani Malhotra, Pravin C Singhal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3253808?pdf=render

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http://europepmc.org/articles/PMC3253808?pdf=render

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