Bevacizumab Augments the Antitumor Efficacy of Infigratinib in Hepatocellular Carcinoma

Bevacizumab Augments the Antitumor Efficacy of Infigratinib in Hepatocellular Carcinoma

The fibroblast growth factor (FGF) signaling cascade is one of the key signaling pathways in hepatocellular carcinoma (HCC). FGF has been shown to augment vascular endothelial growth factor (VEGF)-mediated HCC development and angiogenesis, as well as to potentially lead to resistance to VEGF/VEGF re...

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Bibliographic Details
Main Authors: Thi Bich Uyen Le, Thanh Chung Vu, Rebecca Zhi Wen Ho, Aldo Prawira, Lingzhi Wang, Boon Cher Goh, Hung Huynh
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocellular carcinoma
pan-FGFR inhibitor
angiogenesis inhibitor
invasion
vessel normalization
hypoxia
Online Access:https://www.mdpi.com/1422-0067/21/24/9405

Internet

https://www.mdpi.com/1422-0067/21/24/9405

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