Genotypic Characteristics of Hepatoblastoma as Detected by Next Generation Sequencing and Their Correlation With Clinical Efficacy

Genotypic Characteristics of Hepatoblastoma as Detected by Next Generation Sequencing and Their Correlation With Clinical Efficacy

BackgroundHepatoblastoma (HB) is the most common malignant embryonic liver tumor type in children under 3 years of age. In the present study, the next generation sequencing (NGS) method was used to detect the genotype characteristics of HB and summarize the correlation between the common mutation ge...

Full description

Bibliographic Details
Main Authors: Huimin Hu, Weiling Zhang, Tian Zhi, Jing Li, Yuan Wen, Fan Li, Yanyan Mei, Dongsheng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
hepatoblastoma
CTNNB1
next generation sequencing
tumor mutation burden
PDL1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.628531/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.628531/full

Similar Items