Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse

Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse

The cell cortex that supports the plasma membrane contains spectrin, a protein that interacts with the acto-myosin cytoskeleton. Here, the authors analyze spectrin behavior during cellular mechanoresponse and membrane trafficking, and observe spectrin regulation by myosin-driven contractility.

Bibliographic Details
Main Authors: Andrea Ghisleni, Camilla Galli, Pascale Monzo, Flora Ascione, Marc-Antoine Fardin, Giorgio Scita, Qingsen Li, Paolo Maiuri, Nils C. Gauthier
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18825-7
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spelling doaj-b49028cf2ff84964a7c443b6f61b4c672021-10-10T11:46:16ZengNature Publishing GroupNature Communications2041-17232020-10-0111112110.1038/s41467-020-18825-7Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponseAndrea Ghisleni0Camilla Galli1Pascale Monzo2Flora Ascione3Marc-Antoine Fardin4Giorgio Scita5Qingsen Li6Paolo Maiuri7Nils C. Gauthier8Institute FIRC of Molecular Oncology (IFOM)Institute FIRC of Molecular Oncology (IFOM)Institute FIRC of Molecular Oncology (IFOM)Institute FIRC of Molecular Oncology (IFOM)Institut Jacques Monod, Centre National de la Recherche Scientifique UMR 7592 and Université Paris DiderotInstitute FIRC of Molecular Oncology (IFOM)Institute FIRC of Molecular Oncology (IFOM)Institute FIRC of Molecular Oncology (IFOM)Institute FIRC of Molecular Oncology (IFOM)The cell cortex that supports the plasma membrane contains spectrin, a protein that interacts with the acto-myosin cytoskeleton. Here, the authors analyze spectrin behavior during cellular mechanoresponse and membrane trafficking, and observe spectrin regulation by myosin-driven contractility.https://doi.org/10.1038/s41467-020-18825-7
collection DOAJ
language English
format Article
sources DOAJ
author Andrea Ghisleni
Camilla Galli
Pascale Monzo
Flora Ascione
Marc-Antoine Fardin
Giorgio Scita
Qingsen Li
Paolo Maiuri
Nils C. Gauthier
spellingShingle Andrea Ghisleni
Camilla Galli
Pascale Monzo
Flora Ascione
Marc-Antoine Fardin
Giorgio Scita
Qingsen Li
Paolo Maiuri
Nils C. Gauthier
Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
Nature Communications
author_facet Andrea Ghisleni
Camilla Galli
Pascale Monzo
Flora Ascione
Marc-Antoine Fardin
Giorgio Scita
Qingsen Li
Paolo Maiuri
Nils C. Gauthier
author_sort Andrea Ghisleni
title Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
title_short Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
title_full Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
title_fullStr Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
title_full_unstemmed Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
title_sort complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-10-01
description The cell cortex that supports the plasma membrane contains spectrin, a protein that interacts with the acto-myosin cytoskeleton. Here, the authors analyze spectrin behavior during cellular mechanoresponse and membrane trafficking, and observe spectrin regulation by myosin-driven contractility.
url https://doi.org/10.1038/s41467-020-18825-7
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