Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse

The cell cortex that supports the plasma membrane contains spectrin, a protein that interacts with the acto-myosin cytoskeleton. Here, the authors analyze spectrin behavior during cellular mechanoresponse and membrane trafficking, and observe spectrin regulation by myosin-driven contractility.

Bibliographic Details
Main Authors: Andrea Ghisleni, Camilla Galli, Pascale Monzo, Flora Ascione, Marc-Antoine Fardin, Giorgio Scita, Qingsen Li, Paolo Maiuri, Nils C. Gauthier
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18825-7