Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons

<p>Abstract</p> <p>Background</p> <p>Accumulated evidence suggests that hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) generated in cells during insulin stimulation plays an integral role in insulin receptor signal transduction. The role of insul...

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Bibliographic Details
Main Authors: Pinelis Vsevolod G, Persiyantseva Nadezhda A, Senilova Yana E, Storozhevykh Tatiana P, Pomytkin Igor A
Format: Article
Language:English
Published: BMC 2007-10-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/8/84