SARS-CoV-2 Infection Modulates ACE2 Function and Subsequent Inflammatory Responses in Swabs and Plasma of COVID-19 Patients

Angiotensin converting enzyme 2 (ACE2) is a host ectopeptidase and the receptor for the SARS-CoV-2 virus, albeit virus-ACE2 interaction goes far beyond viral entry into target cells. Controversial data exists linking viral infection to changes in ACE2 expression and function, which might influence t...

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Main Authors: Lucía Gutiérrez-Chamorro, Eva Riveira-Muñoz, Clara Barrios, Vanesa Palau, Maria Nevot, Sònia Pedreño-López, Jordi Senserrich, Marta Massanella, Bonaventura Clotet, Cecilia Cabrera, Oriol Mitjà, Marta Crespo, Julio Pascual, Marta Riera, Ester Ballana
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/9/1715