Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis

Patt1 is a newly identified protein acetyltransferase that is highly expressed in liver. However, the role of Patt1 in liver is still unclear. We generated Patt1 liver-specific knockout (LKO) mice and mainly measured the effect of hepatic Patt1 deficiency on lipid metabolism. Hepatic Patt1 deficienc...

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Bibliographic Details
Main Authors: Yang Liu, Daizhan Zhou, Fang Zhang, Yanyang Tu, Yulei Xia, Hui Wang, Ben Zhou, Yi Zhang, Jingxia Wu, Xiang Gao, Zhishui He, Qiwei Zhai
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520413513