A novel MCF-10A line allowing conditional oncogene expression in 3D culture

A novel MCF-10A line allowing conditional oncogene expression in 3D culture

<p/> <p>Introduction</p> <p>Non-transformed mammary epithelial cell lines such as MCF-10A recapitulate epithelial morphogenesis in three-dimensional (3D) tissue culture by forming acinar structures. They represent an important tool to characterize the biological properties of...

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Bibliographic Details
Main Authors:	Danke Christina, Wöhrle Franziska U, Herr Ricarda, Berens Christian, Brummer Tilman
Format:	Article
Language:	English
Published:	BMC 2011-07-01
Series:	Cell Communication and Signaling
Subjects:	MCF-10A mammary epithelium carcinogenesis <it>BRAF</it> epithelial-mesenchymal transition (EMT) tetracycline-inducible gene expression system apoptosis E-Cadherin KI-67 Caspase-3
Online Access:	http://www.biosignaling.com/content/9/1/17

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