A novel MCF-10A line allowing conditional oncogene expression in 3D culture

A novel MCF-10A line allowing conditional oncogene expression in 3D culture

<p/> <p>Introduction</p> <p>Non-transformed mammary epithelial cell lines such as MCF-10A recapitulate epithelial morphogenesis in three-dimensional (3D) tissue culture by forming acinar structures. They represent an important tool to characterize the biological properties of...

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Bibliographic Details
Main Authors: Danke Christina, Wöhrle Franziska U, Herr Ricarda, Berens Christian, Brummer Tilman
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Cell Communication and Signaling
Subjects:
MCF-10A
mammary epithelium
carcinogenesis
<it>BRAF</it>
epithelial-mesenchymal transition (EMT)
tetracycline-inducible gene expression system
apoptosis
E-Cadherin
KI-67
Caspase-3
Online Access:http://www.biosignaling.com/content/9/1/17

Internet

http://www.biosignaling.com/content/9/1/17

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