Synthesis of PEGylated Human Serum Albumin by Maleimide-Thiol Chemistry and Histopathological Evaluation in a Mice Model of Carrageenan-Induced Inflammation

Occasional incompetence of human serum albumin (HSA) as a plasma expander is linked to severity of the underlying endothelial cell injury so that HSA can readily extravasate if structural integrity of the endothelial is compromised. Consequently, the leaking HSA may exacerbate the oncotic plasma gra...

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Bibliographic Details
Main Authors: Mehdi Hoorang, Alimohammad Tamaddon, Gholamhosein Yousefi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2019-03-01
Series:Trends in Pharmaceutical Sciences
Subjects:
Online Access:http://tips.sums.ac.ir/article_44991_b8b26597533bd0d770c0e90bab8d64ed.pdf