Impairment of neuronal glutamate uptake and modulation of the glutamate transporter GLT-1 induced by retinal ischemia.

Impairment of neuronal glutamate uptake and modulation of the glutamate transporter GLT-1 induced by retinal ischemia.

Excitotoxicity has been implicated in the retinal neuronal loss in several ocular pathologies including glaucoma. Dysfunction of Excitatory Amino Acid Transporters is often a key component of the cascade leading to excitotoxic cell death. In the retina, glutamate transport is mainly operated by the...

Full description

Bibliographic Details
Main Authors: Rossella Russo, Federica Cavaliere, Giuseppe Pasquale Varano, Marco Milanese, Annagrazia Adornetto, Carlo Nucci, Giambattista Bonanno, Luigi Antonio Morrone, Maria Tiziana Corasaniti, Giacinto Bagetta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23936321/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23936321/pdf/?tool=EBI

Similar Items