Fast functional imaging of multiple brain regions in intact zebrafish larvae using Selective Plane Illumination Microscopy

Fast functional imaging of multiple brain regions in intact zebrafish larvae using Selective Plane Illumination Microscopy

The optical transparency and the small dimensions of zebrafish at the larval stage make it a vertebrate model of choice for brain-wide in-vivo functional imaging. However, current point-scanning imaging techniques, such as two-photon or confocal microscopy, impose a strong limit on acquisition speed...

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Bibliographic Details
Main Authors: Thomas ePanier, Sebastian eRomano, Raphaël eOlive, Thomas ePietri, German eSumbre, Raphaël eCandelier, Georges eDebrégeas
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Neural Circuits
Subjects:
Imaging, Three-Dimensional
Neuroimaging
spontaneous activity
Correlation analysis
zebrafish model system
light-sheet imaging
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00065/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00065/full

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