Selective inhibition by antiflamrnin-2 of thromboxane B2 release from isolated and perfused guinea-pig lung

Antiflammin-2 (AF2) is a nonapeptide corresponding to the amino acid residues 246–254 of lipocortin-1 showing anti-inflammatory activity both in vitro and in vivo. The effect of AF2 on the thromboxane B2 (TXB2) and histamine release from isolated and perfused guinea-pig lungs has been studied. AF-2...

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Bibliographic Details
Main Authors: Lidia Sautebin, Giuseppe Cirino, Massimo Di Rosa
Format: Article
Language:English
Published: Hindawi Limited 1992-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935192000383