Locked and Unlocked Nucleosides in Functional Nucleic Acids

Nucleic acids are able to adopt a plethora of structures, many of which are of interest in therapeutics, bio- or nanotechnology. However, structural and biochemical stability is a major concern which has been addressed by incorporating a range of modifications and nucleoside derivatives. This review...

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Bibliographic Details
Main Authors: Birte Vester, Holger Doessing
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/6/4511/