The Intersection of the Genetic Architectures of Orofacial Clefts and Normal Facial Variation

The Intersection of the Genetic Architectures of Orofacial Clefts and Normal Facial Variation

Unaffected relatives of individuals with non-syndromic cleft lip with or without cleft palate (NSCL/P) show distinctive facial features. The presence of this facial endophenotype is potentially an expression of underlying genetic susceptibility to NSCL/P in the larger unselected population. To explo...

Full description

Bibliographic Details
Main Authors: Karlijne Indencleef, Hanne Hoskens, Myoung Keun Lee, Julie D. White, Chenxing Liu, Ryan J. Eller, Sahin Naqvi, George L. Wehby, Lina M. Moreno Uribe, Jacqueline T. Hecht, Ross E. Long, Kaare Christensen, Frederic W. Deleyiannis, Susan Walsh, Mark D. Shriver, Stephen Richmond, Joanna Wysocka, Hilde Peeters, John R. Shaffer, Mary L. Marazita, Greet Hens, Seth M. Weinberg, Peter Claes
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
NSCL/P
endophenotype
genetics
facial morphology
ALSPAC
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.626403/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.626403/full

Similar Items