Search for viral agents in cerebrospinal fluid in patients with multiple sclerosis using real-time PCR and metagenomics.

Multiple sclerosis (MS) is a chronic, immune-mediated demyelinating disease of the central nervous system of unclear etiology, but there is some evidence that viral infections could be responsible for triggering autoimmune mechanisms against myelin. We searched for viral RNA and DNA in cerebrospinal...

Full description

Bibliographic Details
Main Authors: Karol Perlejewski, Iwona Bukowska-Ośko, Małgorzata Rydzanicz, Tomasz Dzieciątkowski, Beata Zakrzewska-Pniewska, Aleksandra Podlecka-Piętowska, Agata Filipiak, Krzysztof Barć, Kamila Caraballo Cortés, Agnieszka Pawełczyk, Marek Radkowski, Tomasz Laskus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240601