Grading amino acid properties increased accuracies of single point mutation on protein stability prediction

<p>Abstract</p> <p>Background</p> <p>Protein stabilities can be affected sometimes by point mutations introduced to the protein. Current sequence-information-based protein stability prediction encoding schemes of machine learning approaches include sparse encoding and a...

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Bibliographic Details
Main Authors: Liu Jianguo, Kang Xianjiang
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/44