Supramolecular Organization of Nonstoichiometric Drug Hydrates: Dapsone

The observed moisture- and temperature dependent transformations of the dapsone (4,4′-diaminodiphenyl sulfone, DDS) 0. 33-hydrate were correlated to its structure and the number and strength of the water-DDS intermolecular interactions. A combination of characterization techniques was used, includin...

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Bibliographic Details
Main Authors: Doris E. Braun, Ulrich J. Griesser
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2018.00031/full