Synthesis and biological properties of the fluorescent ether lipid precursor 1-O-[9′-(1″-pyrenyl)]nonyl-sn-glycerol

Synthesis and biological properties of the fluorescent ether lipid precursor 1-O-[9′-(1″-pyrenyl)]nonyl-sn-glycerol

The synthesis of an ω-pyrene-labeled 1-O-alkyl-sn-glycerol was performed using a chirospecific method starting from R-(−)-2,3-O-isopropylidene-sn-glycerol. The product, 1-O-[9′-(1″-pyrenyl)]nonyl-sn-glycerol (pAG), is a fluorescent ether lipid that has a pyrene moiety covalently attached at the alky...

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Bibliographic Details
Main Authors: Hongying Zheng, Richard I. Duclos, Jr., Conor C. Smith, Harrison W. Farber, Raphael A. Zoeller
Format: Article
Language:English
Published: Elsevier 2006-03-01
Series:Journal of Lipid Research
Subjects:
pyrene
fluorescence
chemical synthesis
ether lipid
plasmalogen
alkylglycerol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520336178

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http://www.sciencedirect.com/science/article/pii/S0022227520336178

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