The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig
Experimental acute gastric ulcer is produced by the intraperitoneal injection of a single dose of indomethacin. Acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers. Its probable mechanism is discussed.
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
1970-12-01
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| Series: | Acta Medica Iranica |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/4116 |
| Summary: | Experimental acute gastric ulcer is produced by the intraperitoneal injection of a single dose of indomethacin. Acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers. Its probable mechanism is discussed.
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| ISSN: | 0044-6025 1735-9694 |