The inhibitory Effect of Acetazoleamide on Indomethacin-induced Gastric Ulcer in Guinea Pig

Experimental acute gastric ulcer is produced by the intraperitoneal injection of a single dose of indomethacin. Acetazoleamide, a potent carbonic anhydrase inhibitor, has significantly prevented the occurrence of these ulcers. Its probable mechanism is discussed.

Bibliographic Details
Main Author: B. Djahanguiri
Format: Article
Language:English
Published: Tehran University of Medical Sciences 1970-12-01
Series:Acta Medica Iranica
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/4116