Ionic liquid catalysed multicomponent synthesis, antifungal activity, docking studies and in silico ADMET properties of novel fused Chromeno-Pyrazolo-Phthalazine derivatives
A series of novel chromeno-pyrazolo[1,2-b]phthalazine-6,9,14(7H)-trione derivatives (4a–k) were designed and prepared using a reusable and efficient catalyst ionic liquid [Bmim]BF4 via one-pot multi-component reaction. Their bioactivity was evaluated against Aspergillus niger and Candida albicans in...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-03-01
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Series: | Journal of Saudi Chemical Society |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319610315000976 |