Ionic liquid catalysed multicomponent synthesis, antifungal activity, docking studies and in silico ADMET properties of novel fused Chromeno-Pyrazolo-Phthalazine derivatives

A series of novel chromeno-pyrazolo[1,2-b]phthalazine-6,9,14(7H)-trione derivatives (4a–k) were designed and prepared using a reusable and efficient catalyst ionic liquid [Bmim]BF4 via one-pot multi-component reaction. Their bioactivity was evaluated against Aspergillus niger and Candida albicans in...

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Bibliographic Details
Main Authors: P. Sagar Vijay Kumar, L. Suresh, G.V.P. Chandramouli
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610315000976