Alterations in neurotransmitter levels and transcription factor expression following intranasal buprenorphine administration

Alterations in neurotransmitter levels and transcription factor expression following intranasal buprenorphine administration

Buprenorphine is an opioid drug used in the management of pain and the treatment opioid addiction. Like other opioids, it is believed that it achieves these effects by altering functional neurotransmitter pathways and the expression of important transcription factors; cyclic AMP response element-bin...

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Bibliographic Details
Main Authors: Sanelisiwe P. Xhakaza, Leon J. Khoza, Advaitaa M. Haripershad, Terisha Ghazi, Shanel Dhani, Cosmas Mutsimhu, Molopa J. Molopa, Nithia P. Madurai, Lorna Madurai, Sanil D. Singh, Nirmala D. Gopal, Hendrik G. Kruger, Thavendran Govender, Anil Chuturgoon, Tricia Naicker, Sooraj Baijnath
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Buprenorphine
Opioid addiction
Brain-derived neurotrophic factor (BDNF)
Cyclic AMP response element-binding protein (CREB)
Neurotransmitters
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221003000

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http://www.sciencedirect.com/science/article/pii/S0753332221003000

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