TAE226, a dual inhibitor of focal adhesion kinase and insulin‐like growth factor‐I receptor, is effective for Ewing sarcoma

TAE226, a dual inhibitor of focal adhesion kinase and insulin‐like growth factor‐I receptor, is effective for Ewing sarcoma

Abstract The outcomes for relapsed and metastatic Ewing sarcoma (EWS) is extremely poor. Therefore, it is important to identify the tumor‐specific targets in these intractable diseases. High focal adhesion kinase (FAK) transcript expression levels in EWS cell lines are known. TAE226 is a dual inhibi...

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Bibliographic Details
Main Authors: Hiroshi Moritake, Yusuke Saito, Daisuke Sawa, Naoki Sameshima, Ai Yamada, Mariko Kinoshita, Sachiyo Kamimura, Takao Konomoto, Hiroyuki Nunoi
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Cancer Medicine
Subjects:
Ewing sarcoma
focal adhesion kinase
insulin‐like growth factor‐I receptor
metastasis
TAE226
Online Access:https://doi.org/10.1002/cam4.2647

Internet

https://doi.org/10.1002/cam4.2647

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