A strategic expression method of miR-29b and its anti-fibrotic effect based on RNA-sequencing analysis.

Tissue fibrosis is a significant health issue associated with organ dysfunction and failure. Increased deposition of collagen and other extracellular matrix (ECM) proteins in the interstitial area is a major process in tissue fibrosis. The microRNA-29 (miR-29) family has been demonstrated as anti-fi...

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Bibliographic Details
Main Authors: Xiaoming Fan, Yingnyu Gao, Xiaolu Zhang, Haroon Y Lughmani, David J Kennedy, Steven T Haller, Sandrine V Pierre, Joseph I Shapiro, Jiang Tian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244065