NUSAP1 Promotes Gastric Cancer Tumorigenesis and Progression by Stabilizing the YAP1 Protein

NUSAP1 Promotes Gastric Cancer Tumorigenesis and Progression by Stabilizing the YAP1 Protein

The Yes-associated protein (YAP1) is a main effector of the canonical Hippo pathway, which contributes greatly to tumor initiation, progression, and metastasis in multiple cancers, including gastric cancer (GC). Due to limited knowledge of YAP1 upregulation in cancer, it is a great challenge of ther...

Full description

Bibliographic Details
Main Authors: Hui Guo, Jianping Zou, Ling Zhou, Min Zhong, Yan He, Shanshan Huang, Jun Chen, Junhe Li, Jianping Xiong, Ziling Fang, Xiaojun Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
NUSAP1
YAP1
protein stability
tumorigenesis and progression
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.591698/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.591698/full

Similar Items