Degranulation of cutaneous mast cells induces transendothelial transport and local accumulation of plasma LDL in rat skin in vivo

In severe hypercholesterolemia and sometimes even in normolipemia, lipoprotein-derived cholesterol accumulates in the skin, forming xanthomas, but the local factors triggering this accumulation are not known. We therefore studied the effect of immunoglobulin E (IgE)-mediated stimulation of cutaneous...

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Bibliographic Details
Main Authors: H Ma, P T Kovanen
Format: Article
Language:English
Published: Elsevier 1997-09-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520371625