Role of Prostaglandin D2 and Its Receptors in the Pathophysiology of Asthma

Role of Prostaglandin D2 and Its Receptors in the Pathophysiology of Asthma

Prostaglandin D2 (PGD2) is one of the most abundant lipid mediators present in the airways of asthmatics. However, little was known of the role it plays in the pathophysiology of asthma, until the identification of DP (DP1, PTGDR) and CRTH2 (DP2), two PGD2-specific transmembrane receptors with diffe...

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Bibliographic Details
Main Authors: Tsuyoshi Oguma, Koichiro Asano, Akitoshi Ishizaka
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Allergology International
Subjects:
asthma
CRTH2
DP
eosinophils
lipid mediators
single nucleotide polymorphisms
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015307930

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http://www.sciencedirect.com/science/article/pii/S1323893015307930

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