SoxD transcription factor deficiency in Schwann cells delays myelination in the developing peripheral nervous system

Abstract The three SoxD proteins, Sox5, Sox6 and Sox13, represent closely related transcription factors with important roles during development. In the developing nervous system, SoxD proteins have so far been primarily studied in oligodendroglial cells and in interneurons of brain and spinal cord....

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Bibliographic Details
Main Authors: Ella Ittner, Anna C. Hartwig, Olga Elsesser, Hannah M. Wüst, Franziska Fröb, Miriam Wedel, Margit Schimmel, Ernst R. Tamm, Michael Wegner, Elisabeth Sock
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93437-9