A recursive framework for predicting the time-course of drug sensitivity

Abstract The biological processes involved in a drug’s mechanisms of action are oftentimes dynamic, complex and difficult to discern. Time-course gene expression data is a rich source of information that can be used to unravel these complex processes, identify biomarkers of drug sensitivity and pred...

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Bibliographic Details
Main Authors: Cheng Qian, Amin Emad, Nicholas D. Sidiropoulos
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-74725-2