Inference of differentiation time for single cell transcriptomes using cell population reference data

Inference of differentiation time for single cell transcriptomes using cell population reference data

Single cell transcriptome data can be used to determine developmental lineage trajectories. Here the authors map single cell transcriptomes onto a differentiation trajectory defined by cell population transcriptomes and show that cell cycle regulators have a role in differentiation timing.

Bibliographic Details
Main Authors: Na Sun, Xiaoming Yu, Fang Li, Denghui Liu, Shengbao Suo, Weiyang Chen, Shirui Chen, Lu Song, Christopher D. Green, Joseph McDermott, Qin Shen, Naihe Jing, Jing-Dong J. Han
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01860-2

Internet

https://doi.org/10.1038/s41467-017-01860-2

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