Synthesis and in vitro antimycobacterial potential of novel hydrazones of eugenol

Fifty one hydrazone derivatives of eugenol were designed and docked with 2NSD and 2X22 (enzymes of H37Rv strain) using Schrodinger v7.4. The selective ten hydrazone derivatives (4, 5, 11, 18, 30, 34, 35, 37, 42, and 45) of eugenol were synthesized via esterification, hydrazination and treatment with...

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Bibliographic Details
Main Authors: Sachin H. Rohane, Ashlesha J. Chauhan, Neeraj Kumar Fuloria, Shivkanya Fuloria
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535219301066