Sialic acid: a sweet swing between mammalian host and Trypanosoma cruzi

Commonly found at the outermost ends of complex carbohydrates in extracellular medium or on outer cell membranes, sialic acids play important roles in a myriad of biological processes. Mammals synthesize sialic acid through a complex pathway, but Trypanosoma cruzi, the agent of Chagas’ disease, evol...

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Bibliographic Details
Main Authors: Leonardo eFreire-de-Lima, Isadora A. Oliveira, Jorge L. Neves, Luciana L. Penha, Frederico eAlisson-Silva, Wagner B. Dias, Adriane Regina Todeschini
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00356/full