Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma

Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma

Abstract Background Non-synonymous mutations altering tumor suppressor genes and oncogenes are widely studied. However, synonymous mutations, which do not alter the protein sequence, are rarely investigated in melanoma genome studies. Methods We explored the role of somatic synonymous mutations in m...

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Bibliographic Details
Main Authors: Di Zhang, Junfeng Xia
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Medical Genomics
Subjects:
Melanoma
Synonymous mutations
Regulatory elements
Online Access:http://link.springer.com/article/10.1186/s12920-020-0685-2

Internet

http://link.springer.com/article/10.1186/s12920-020-0685-2

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