Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

Kim Valette et al. perform a genomic study on asthma integrating genome-wide association study, functional mapping using lung and blood transcriptome-wide profiles, as well as Mendelian randomization. They show candidate causal genes expressed in lung and blood tissues that are putative therapeutic...

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Bibliographic Details
Main Authors: Kim Valette, Zhonglin Li, Valentin Bon-Baret, Arnaud Chignon, Jean-Christophe Bérubé, Aida Eslami, Jennifer Lamothe, Nathalie Gaudreault, Philippe Joubert, Ma’en Obeidat, Maarten van den Berge, Wim Timens, Don D. Sin, David C. Nickle, Ke Hao, Catherine Labbé, Krystelle Godbout, Andréanne Côté, Michel Laviolette, Louis-Philippe Boulet, Patrick Mathieu, Sébastien Thériault, Yohan Bossé
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02227-6

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