Honokiol inhibits arecoline-induced oral fibrogenesis through transforming growth factor-β/Smad2/3 signaling inhibition

Background/purpose: The habit of areca nut chewing has been regarded as an etiological factor of precancerous oral submucous fibrosis (OSF). In the present study, we aimed to evaluate the anti-fibrosis effect of honokiol, a polyphenolic component derived from Magnolia officinalis. Methods: The cytot...

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Bibliographic Details
Main Authors: Pei-Yin Chen, Dennis Chun-Yu Ho, Yi-Wen Liao, Pei-Ling Hsieh, Kai-Hsi Lu, Lo-Lin Tsai, Sheng-Hua Su, Cheng-Chia Yu
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664621001698