Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria

Polymyxins are polycationic antimicrobial peptides that are currently the last-resort antibiotics for the treatment of multidrug-resistant, Gram-negative bacterial infections. The reintroduction of polymyxins for antimicrobial therapy has been followed by an increase in reports of resistance among G...

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Bibliographic Details
Main Authors: Abiola Olumuyiwa Olaitan, Serge eMorand, Jean-Marc eRolain
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00643/full