Hydrolysis, polarity, and conformational impact of C-terminal partially fluorinated ethyl esters in peptide models
Fluorinated moieties are highly valuable to chemists due to the sensitive NMR detectability of the 19F nucleus. Fluorination of molecular scaffolds can also selectively influence a molecule’s polarity, conformational preferences and chemical reactivity, properties that can be exploited for various c...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2017-11-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.13.241 |